Bellevue Asia Pacific Healthcare (Lux)
Access to defensive growth driven by increased demand for healthcare products and services due to rising share of the middle class
Asian Healthcare market is growing twice as fast as corresponding GDP
Above-average performance - complementary building block for an Asia investor
Explained in 90 seconds
Please find a more detailed description of share classes here.
Investment Focus
ISIN-No. LU1587984680
This fund invests in healthcare stocks throughout the Asia-Pacific region. Its investment universe consists of generics producers, pharma and biotech companies, medical technology and services firms. Experienced sector specialists focus on profitable companies that have a well-established product portfolio. Investments are made based on fundamental research analysis.
Indexed performance (as at: 02.06.2023)
NAV: USD 170.02 (31.05.2023)
Rolling performance (01.06.2023)
I-USD | MSCI Asia Pacific Healthcare Index | MSCI Asia Pacific Index | |
01.06.2022 - 01.06.2023 | -1.55% | 2.76% | -3.14% |
01.06.2021 - 01.06.2022 | -37.29% | -29.12% | -17.88% |
29.05.2020 - 01.06.2021 | 29.36% | 18.62% | 42.59% |
31.05.2019 - 29.05.2020 | 38.88% | 33.75% | 1.26% |
Annualized performance (01.06.2023)
I-USD | MSCI Asia Pacific Healthcare Index | MSCI Asia Pacific Index | |
1 year | -1.55% | 2.76% | -3.14% |
3 years | -7.20% | -4.74% | 4.27% |
5 years | -0.69% | 0.71% | 0.84% |
Since Inception p.a. | 5.44% | 5.37% | 3.55% |
Cumulative performance (01.06.2023)
I-USD | MSCI Asia Pacific Healthcare Index | MSCI Asia Pacific Index | |
1M | -1.78% | -0.26% | -0.29% |
YTD | -1.75% | 0.89% | 3.38% |
1 year | -1.55% | 2.76% | -3.14% |
3 years | -20.13% | -13.60% | 13.41% |
5 years | -3.39% | 3.60% | 4.28% |
Since Inception | 38.11% | 37.57% | 23.71% |
Annual performance
I-USD | MSCI Asia Pacific Healthcare Index | MSCI Asia Pacific Index | |
2022 | -23.21% | -16.97% | -16.88% |
2021 | -12.88% | -16.17% | -1.87% |
2020 | 45.04% | 33.01% | 19.70% |
2019 | 23.61% | 30.06% | 19.36% |
Facts & Key figures
Investment Focus
The fund’s aim is to achieve capital growth in the long term. The Bellevue Asia Pacific Healthcare fund invests in healthcare stocks of companies that have their registered office or carry out the majority of their economic activity in the healthcare markets of the Asia-Pacific region. Show moreShow less
Investment suitability & Risk
Low risk
High risk
General Information
Investment Manager | Bellevue Asset Management AG |
Custodian | RBC Investor Services, Luxembourg |
Fund Administrator | RBC Investor Services, Luxembourg |
Auditor | PriceWaterhouseCoopers |
Launch date | 28.04.2017 |
Year end closing | 30. Jun |
NAV Calculation | Daily "Forward Pricing" |
Cut of time | 09:00 CET |
Management Fee | 0.90% |
Subscription Fee (max.) | 5.00% |
Performance Fee | 10.00% (with High Water Mark) |
ISIN number | LU1587984680 |
Valor number | 36225512 |
Bloomberg | BEAAPIU LX |
WKN | A2DPA1 |
Total expense ratio (TER) | 1.51% (31.05.2023) |
Legal Information
Legal form | Luxembourg UCITS V SICAV |
SFDR category | Article 8 |
Redemption period | Daily |
Key data (31.05.2023, base currency USD)
Beta | 0.84 |
Volatility | 18.30 |
Tracking error | 10.64 |
Active share | 46.52 |
Correlation | 0.83 |
Sharpe ratio | -0.44 |
Information ratio | -0.33 |
Jensen's alpha | -4.13 |
No. of positions | 28 |
Portfolio
Top 10 positions
Market capitalization
Geographic breakdown
Breakdown by sector
Currency
Opportunities & Risks
Opportunities
- Access to defensive growth – Asia’s emerging countries are facing aging populations and changing lifestyles.
- An interesting combination of investments in Asian emerging markets and Japanese cutting-edge technology.
- Broad spread across different sectors and company sizes in the Asia-Pacific healthcare industry.
- Attractive valuations compared with the projected medium to long-term growth.
- Bellevue Healthcare Team – top-performing pioneer in the management of healthcare portfolios in emerging markets.
Risks
- The fund invests in equities. Equities are subject to price fluctuations and so are also exposed to the risk of price losses.
- Investing in emerging markets entails the additional risk of political and social instability.
- The fund invests in foreign currencies, which means a corresponding degree of currency risk against the reference currency.
- The fund may invest in China A equities. This entails the risk of supervisory changes, volume caps and operating restrictions which may lead to a higher counterparty risk.
- The fund may invest a proportion of its assets in financial instruments that might under certain circumstances have a relatively low level of liquidity, which can in turn affect the fund’s liquidity.
Review / Outlook
The Chinese biotech company Legend Biotech and its partner Johnson & Johnson published exciting Phase III data on their cell therapy Carvykti in multiple myeloma. In the CARTITUDE-4 study, in which 419 patients had been enrolled, 208 were treated with Carvykti and 211 received standard of care treatments after having received one to three prior lines of standard therapy. Legend’s cell therapy slashed the risk of tumor progression or death by a 74% compared to standard of care (hazard ratio of 0.26). This represents an entirely new playing field in the early treatment of multiple myeloma compared to both standard therapy and the only other approved fifth-line myeloma treatment (Abecma from Bristol-Myers Squibb). This news report was based on information from an interim analysis as of November 1, 2022, so conclusive data regarding progression-free survival was not available. Calculations of median PFS are around 35-40 months. Some doctors have said the drug might even be able to cure patients with multiple myeloma. It seems very likely that Carvykti will be approved as a second-line treatment by the end of this year and will then establish a high penetration rate in this indication. Its high price tag of more than USD 400000 per treatment should not be a problem because most patients will not need any other treatment for three or more years. The side effect profile was also favorable. Although 76% of patients experienced cytokine release syndrome, the vast majority of these episodes were mild.
This news is also very encouraging for Legend's ongoing studies of Carvykti (CARTITUDE-5&6) as a first-line treatment for myeloma. Carvykti’s peak sales potential is projected at above USD 5 bn. We are staying invested in the stock.
A position in Genscript was opened during the past month and existing positions in Eisai and Sysmex were increased. Positions in Fisher Paykel, Wuxi AppTec and Shin Nippon Biomedical were closed.
Japan, which has been referred to as “the world's demographic laboratory”, has championed cutting-edge innovation for decades. The Land of the Rising Sun boasts technology leadership in numerous fields, ranging from therapeutic antibody technology, immunotherapy and robotics to digitalization, diagnostics and medical imaging systems. The fund offers defensive access to Asian emerging markets as well as exciting investment opportunities in technology leaders throughout the entire region. It invests in the entire healthcare system value chain, from generic drug producers and biotechnology companies to medical device manufacturers and digital health specialists.
Documents
Past performance is not a reliable indicator of future results and can be misleading. As the sub-fund is denominated in a currency that may differ than an investor’s base currency, changes in the rate of exchange may have an adverse effect on prices and incomes. Performance is shown net of fees and expenses for the relevant share class over the reference period. Show moreShow less