Bellevue Asia Pacific Healthcare (Lux)
Access to defensive growth driven by increased demand for healthcare products and services due to rising share of the middle class
Asian Healthcare market is growing twice as fast as corresponding GDP
Above-average performance - complementary building block for an Asia investor
Explained in 90 seconds
Please find a more detailed description of share classes here.
Investment Focus
ISIN-No. LU1587984680
This fund invests in healthcare stocks throughout the Asia-Pacific region. Its investment universe consists of generics producers, pharma and biotech companies, medical technology and services firms. Experienced sector specialists focus on profitable companies that have a well-established product portfolio. Investments are made based on fundamental research analysis.
Indexed performance (as at: 02.10.2023)
NAV: USD 158.19 (28.09.2023)
Rolling performance (30.09.2023)
I-USD | MSCI Asia Pacific Healthcare Index | MSCI Asia Pacific Index | |
30.09.2022 - 30.09.2023 | 0.92% | -0.17% | 16.08% |
30.09.2021 - 30.09.2022 | -39.95% | -33.85% | -27.75% |
30.09.2020 - 30.09.2021 | 5.35% | 5.74% | 18.28% |
30.09.2019 - 30.09.2020 | 55.13% | 38.76% | 11.21% |
Annualized performance (30.09.2023)
I-USD | MSCI Asia Pacific Healthcare Index | MSCI Asia Pacific Index | |
1 year | 0.92% | -0.17% | 16.08% |
3 years | -13.89% | -11.28% | -0.27% |
5 years | -1.84% | -0.34% | 1.38% |
Since Inception p.a. | 3.83% | 3.14% | 3.34% |
Cumulative performance (30.09.2023)
I-USD | MSCI Asia Pacific Healthcare Index | MSCI Asia Pacific Index | |
1M | -2.16% | -4.26% | -2.38% |
YTD | -9.41% | -1.66% | 3.23% |
1 year | 0.92% | -0.17% | 16.08% |
3 years | -36.16% | -30.17% | -0.79% |
5 years | -8.86% | -1.66% | 7.11% |
Since Inception | 27.35% | 22.00% | 23.52% |
Annual performance
I-USD | MSCI Asia Pacific Healthcare Index | MSCI Asia Pacific Index | |
2022 | -23.21% | -24.46% | -16.88% |
2021 | -12.88% | -16.17% | -1.87% |
2020 | 45.04% | 33.01% | 19.70% |
2019 | 23.61% | 30.06% | 19.36% |
Facts & Key figures
Investment Focus
The fund’s aim is to achieve capital growth in the long term. The Bellevue Asia Pacific Healthcare fund invests in healthcare stocks of companies that have their registered office or carry out the majority of their economic activity in the healthcare markets of the Asia-Pacific region. Show moreShow less
Investment suitability & Risk
Low risk
High risk
General Information
Investment Manager | Bellevue Asset Management AG |
Custodian | RBC Investor Services, Luxembourg |
Fund Administrator | RBC Investor Services, Luxembourg |
Auditor | PriceWaterhouseCoopers |
Launch date | 28.04.2017 |
Year end closing | 30. Jun |
NAV Calculation | Daily "Forward Pricing" |
Cut of time | 09:00 CET |
Management Fee | 0.90% |
Subscription Fee (max.) | 5.00% |
Performance Fee | 10.00% (with High Water Mark) |
ISIN number | LU1587984680 |
Valor number | 36225512 |
Bloomberg | BEAAPIU LX |
WKN | A2DPA1 |
Total expense ratio (TER) | 1.48% (29.09.2023) |
Legal Information
Legal form | Luxembourg UCITS V SICAV |
SFDR category | Article 8 |
Redemption period | Daily |
Portfolio
Top 10 positions
Market capitalization
Geographic breakdown
Breakdown by sector
Currency
Benefits & Risks
Benefits
- Access to defensive growth – Asia’s emerging countries are facing aging populations and changing lifestyles.
- An interesting combination of investments in Asian emerging markets and Japanese cutting-edge technology.
- Broad spread across different sectors and company sizes in the Asia-Pacific healthcare industry.
- Attractive valuations compared with the projected medium to long-term growth.
- Bellevue Healthcare Team – top-performing pioneer in the management of healthcare portfolios in emerging markets.
Risks
- The fund invests in equities. Equities are subject to price fluctuations and so are also exposed to the risk of price losses.
- Investing in emerging markets entails the additional risk of political and social instability.
- The fund invests in foreign currencies, which means a corresponding degree of currency risk against the reference currency.
- The fund may invest in China A equities. This entails the risk of supervisory changes, volume caps and operating restrictions which may lead to a higher counterparty risk.
- The fund may invest a proportion of its assets in financial instruments that might under certain circumstances have a relatively low level of liquidity, which can in turn affect the fund’s liquidity.
Review / Outlook
Daiichi Sankyo and its partner AstraZeneca announced in July the results of the Phase III TROPION-Lung01 trial of the anti-TROP2 antibody drug conjugate Dato-DXd as a second-line (or later-line) treatment option for patients with non-small cell lung cancer. As expected, detailed clinical data was not disclosed, but Dato-DXd met its dual primary endpoint of a statistically significant improvement in progression-free survival compared to docetaxel, the current standard of care chemotherapy. Data for the other primary endpoint, overall survival, was not yet mature, but an early trend was observed in favor of Dato-DXd. We expect detailed data to be published in September or October. Unfortunately, some deaths were also reported, in contrast to previous trials of Dato-DXd. However, it is not clear whether these deaths were related to the drug, but this could raise investor concerns about the drug’s safety profile.
Legend Biotech’s partner, Johnson & Johnson, reported that the Carvykti cell therapy generated sales of USD 117 mn in the second quarter of 2023. That beat market expectations by more than 40%. The fast growth was primarily attributed to the expansion of in-house production capacity and to production process improvements. Increased in-house production of lentiviral vectors has been crucial in this regard. The aim is to establish Carvykti in earlier lines of treatment by the end of 2023. Studies to this end are currently under way. We are confident that this multiple myeloma cell therapy can generate peak annual sales in excess of USD 5 bn.
As expected, Eisai and Biogen’s Alzheimer's drug Leqembi was granted full FDA approval. Surprisingly, the FDA added its stringent safety warning about side effects to Leqembi’s label. Furthermore, genetic testing was recommended before starting treatment. This could lead to initially low sales of Leqembi. Surprisingly, the head of the company’s US operations and its neurology business at Eisai announced his retirement at the end of the month. His position will be filled by the son of the company's CEO. For these reasons, we liquidated the entire position.
New positions were opened in Wuxi Apptec, Telix Pharma, New Horizon and Pharmaessentia during the past month and existing positions in Wuxi Biologics, Otsuka and Sun Pharma were increased. Eisai is no longer in the fund's portfolio and shareholdings of Takeda, Dr. Reddy's and Daiichi Sankyo were reduced.
Japan, which has been referred to as “the world's demographic laboratory”, has championed cutting-edge innovation for decades. The Land of the Rising Sun boasts technology leadership in numerous fields, ranging from therapeutic antibody technology, immunotherapy and robotics to digitalization, diagnostics and medical imaging systems. The fund offers defensive access to Asian emerging markets as well as exciting investment opportunities in technology leaders throughout the entire region. It invests in the entire healthcare system value chain, from generic drug producers and biotechnology companies to medical device manufacturers and digital health specialists.
Documents
Past performance is not a reliable indicator of future results and can be misleading. As the sub-fund is denominated in a currency that may differ than an investor’s base currency, changes in the rate of exchange may have an adverse effect on prices and incomes. Performance is shown net of fees and expenses for the relevant share class over the reference period. Show moreShow less